TEL AVIV – Critically ill COVID-19 patients recovered rapidly from respiratory failure after three days of treatment with RLF-100, a therapy granted fast-track designation in the United States, two drug companies said on Sunday.
Geneva-based Relief Therapeutics Holdings AG RFLB.S has a patent for RLF-100, or aviptadil, a synthetic form of a natural peptide that protects the lung. U.S.-Israeli NeuroRx Inc partnered with Relief to develop the drug in the United States.
In June the U.S. Food and Drug Administration granted fast-track designation to RLF-100 for treatment of respiratory distress in COVID-19.
While a Phase 2/3 clinical trial with 70 patients is ongoing, RLF-100 is being administered on an emergency basis to some patients who are too ill to be admitted to the trial.
The first report of rapid recovery under emergency use was posted by doctors from Houston Methodist Hospital, the companies said in a joint statement.
It said a 54-year-old man who developed COVID-19 while being treated for rejection of a double lung transplant came off a ventilator within four days of treatment with RLF-100.
Similar results were subsequently seen in more than 15 patients treated under emergency use, the companies said.
The two companies also said independent researchers in a biocontainment laboratory in Brazil reported that aviptadil blocked replication of the SARS coronavirus in human lung cells and immune cells.
Zrkgrp says
lasix price – prograf 5mg cost cheap captopril 25mg
Cytqgp says
purchase flagyl without prescription – oxytetracycline 250 mg sale order zithromax online
Jlqmve says
buy ampicillin generic ampicillin ca buy cheap amoxicillin
Msrxbo says
flagyl sale – buy cleocin 300mg online buy generic azithromycin 250mg
Qozqnv says
ciprofloxacin pills – tinidazole where to buy buy erythromycin sale
Kweykx says
buy ciprofloxacin generic – buy generic cipro augmentin 625mg oral
Fbvwxd says
buy ciprofloxacin 500mg pill – ethambutol 600mg without prescription augmentin 625mg cost
Vhbfpz says
purchase ampicillin sale where can i buy ampicillin amoxil online buy
Buzqor says
buy generic zofran 4mg spironolactone over the counter spironolactone online buy
Wocwtv says
imitrex 50mg brand purchase imitrex online levofloxacin order online
Awravg says
tamsulosin 0.4mg ca celecoxib 100mg ca buy celecoxib medication
Boxxjo says
buy mobic 15mg sale celecoxib 100mg price buy celebrex tablets